Glenn R. Gaudette

John W. Kozarich 鈥�71 Chair of the Department of Engineering

Professor

Photo of Glenn R. Gaudette

Glenn R. Gaudette

Contact

245 Beacon Street, Room 511

Telephone: 617-552-2049

Email: glenn.gaudette@bc.edu

Profile

Glenn Gaudette, a biomedical engineer who has pioneered the use of plants as scaffolding for heart regeneration, has been named the inaugural chair of Boston College鈥檚 new Engineering Department, which will integrate 香蕉秀鈥檚 liberal arts focus with a human-centered engineering curriculum to prepare students to find solutions that address critical human needs.

His research, supported by the National Institutes of Health and the National Science Foundation, aims to develop a treatment for the millions of Americans suffering from myocardial infarction and other cardiovascular diseases. His work is also focused on the cultivation of protein products as sustainable food sources with reduced environmental impact.

Selected Publications

  1. Gershlak JR, Hernandez S, Fontana G, Perreault LR, Hansen KJ, Larson SA, Binder BY, Dolivo DM, Yang T, Dominko T, Rolle MW, Weathers PJ, Medina-Bolivar F, Cramer CL, Murphy WL,聽Gaudette GR. Crossing kingdoms: Using decellularized plants as perfusable tissue engineering scaffolds.聽Biomaterials. 2017 May;125:13-22.
  2. Fontana G, Gershlak J, Adamski M, Lee JS, Matsumoto S, Le HD, Binder B, Wirth J,聽Gaudette G, Murphy WL. Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture.聽Advanced Healthcare Materials. 2017, 6(8).
  3. Jank BJ, Goverman J, Guyette JP, Charest JM, Randolph MA,聽Gaudette GR, Gershlak JR, Purschke M, Javorsky E, Nazarian RM, Leonard DA, Cetrulo CL, Austen WG Jr, Ott HC. Creation of a Bioengineered Skin Flap Scaffold with a Perfusable Vascular Pedicle.聽Tissue Engineering Part A. 2017, 23(13-14):696-707.
  4. Hansen KJ, Favreau JT, Gershlak JR, Laflamme MA, Albrecht DR,聽Gaudette GR. Optical Method to Quantify Mechanical Contraction and Calcium Transients of Human Pluripotent Stem Cell-Derived Cardiomyocytes.聽Tissue Engineering Part C: Methods. 2017, 23(8): 445-454.
  5. Hansen KJ, Laflamme MA,聽Gaudette GR. Development of a Contractile Cardiac Fiber from Pluripotent Stem Cell Derived Cardiomyocytes.聽Frontiers in Cardiovascular Medicine.聽2018 5, 52.
  6. Adamski M, Fontana G, Gershlak JR,聽Gaudette GR, Le HD, Murphy WL. Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications.聽Journal of Visual Experiments. (135), e57586, 2018.
  7. DiBiasio D, Boudreau K, Dodson L, Quinn P, Bergendahl J, Sullivan JM,聽Gaudette GR, Abel C, Robinson LA, Wodin-Schwartz S. Many Hands on the Elephant: How a Transdisciplinary Team Assesses an Integrative Course. 2018 ASEE Annual Conference & Exposition, 2018,聽.
  8. Hutcheson JD, Goergen CJ, Schoen FJ, Aikawa M, Zilla P, Aikawa E,聽Gaudette GR. After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective from the International Society for Applied Cardiovascular Biology.聽Frontiers in Cardiovascular Medicine. 2019, 6 (e-pub).
  9. Carlson C, Polizzotto L,聽Gaudette GR. The 鈥淣A香蕉秀's鈥� of Value Propositions.聽IEEE Engineering Management Review.聽2019, 47(3), 15-20.
  10. Moser PT, Gerli M, Diercks GR, Evangelista-Leite D, Charest JM, Gershlak JR, Ren X, Gilpin SE, Jank BJ,聽Gaudette GR, Hartnick CJ, Ott HC. Creation of Laryngeal Grafts from Primary Human Cells and Decellularized Laryngeal Scaffolds.聽Tissue Engineering Part A.聽2020, 26:543-555.
  11. Robbins ER, Pins GD, Laflamme MA,聽Gaudette GR. Creation of a contractile biomaterial from a decellularized spinach leaf without ECM protein coating: An in vitro study.聽Journal of Biomedical Materials Research Part A. 2020, 108 (10), 2123-2132.
  12. Jones JD, Rebello AS,聽Gaudette GR. Decellularized spinach: An edible scaffold for lab-grown meat.聽Food Bioscience聽2021, 41, 100986.

Patents

  • Systems and methods for mapping and ablation in the bladder聽(with M Boden, S Nagale, Y Mendelson, D Cavallaro*, T Richardson*, T Hickey*, R Shuraim*, D Goksun*)
    US Patent # 11,083,516; Issued August 10, 2021; * = undergraduate students
  • Decellularization of Plant Cell Culture Materials for Tissue Engineering and Drug Delivery聽(with J Coburn, N Phan)
    US Patent # 11,110,203; Issued: September 7, 2021
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